A Syllabus for the Proposed Pharmacy Curriculum SY 2005-2006
Course Title : Research and Thesis Writing 1 & 2
Course Number :
Credit Units : 1st Semester - Research & Thesis Writing 1: 3 units (1units lecture, 2 unit laboratory)
2nd Semester - Research & Thesis Writing 2: 2 units (1units laboratory)
Course Description : This course deals with the specific problem related to pharmaceutical sciences that would be worthwhile to investigate during the laboratory work. It will comprise actual pharmaceutical and pharmacologic principles and animal testing which will be conducted inside the laboratory. It also includes the thesis writing after experimental results are completed.
Prerequisite(s) : Senior standing
General Objectives : At the end of the course, the students should be able to:
1. Relate the purpose(s) of choosing the problem for search.
2. Discuss the steps of the procedure for the investigation.
3. Present, organize, analyze and interpret the data collected and write scientifically.
4. Begin an independent study using logical thinking and scientific methods.
5. Gather new knowledge or data from primary or first-hand sources and not merely restate or reorganize what is already known or has been written.
6. Perform successfully the experimental procedures in the laboratory portion of the subject.
7. Present and defend a written output of the research.
Course Outline :
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
First Semester
1. Recall the principles of research methods and thesis writing.
2. Propose a research problem
Unit 1 – Introduction to Research and Thesis Writing
A. Orientation to the course objectives and content
B. Form and Style
C. The research problem
Laboratory
a. Research and referencing
10 hrs + 6 hrs lab
Individual or group research on problems/topics chosen as reported in class
Quality of topic chosen and reporting in class
Submission of research proposal reports
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
1. To involve students in extensive literature survey using local and international research papers.
2. Evaluate the different types of literature needed in the study
3. Familiarize on bibliography formats and catalogue
1. Identify the different types of sampling
2. Select appropriate statistical tools and formula
3. State the different types of research methodology
4. Defend the research proposal
Second Semester
1. Perform needed experimental procedure for laboratory testing and product formulation or conduct surveys
2. Analyze, present and evaluate data obtained from the experiment, surveys and questionnaire
1. Defend the research and do the necessary corrections and recommendations
2. Submit the final manuscript
Unit 2 – Review of Related Literature
A. Types of Literature
B. Bibliography and Cataloguing
Laboratory
a. Research and referencing
b. Informatics
Unit 3 – Review of Basic Statistics and Research Methodology
A. Sampling
B. Statistical formulas
C. Statistical tools
D. Types of research methodology
Laboratory
a. Finalization of the research
b. Proposal defense
Unit 4 – Laboratory, Checking / Monitoring of the laboratory work until completion of the Thesis
Unit 5 - Thesis Writing and Preparation of the Final Manuscript and Oral Defense as scheduled
10 hrs + 6 hrs lab
8 hrs + 21 hrs lab
18 hrs + 27 hrs lab
80 hrs
28 hrs
Class participation in giving comments, remarks and/or suggestions on reports
Lecture
Power Point Presentation,
Information Communication Technology (ICT)
Integration
Assigned readings,
Class group discussions
Final oral examination/defense of the thesis, submission of the bound form of the approved manuscript
Written Examination and Oral defense of the research proposal.
Oral defense of the thesis problem
Completeness and neatness of the bound thesis submitted
References : Books on Medicinal Plants authored by E. Quisumbing, de Padua and other published new books, both local and foreign sources
Philippine Formulary
USP/NF, latest edition
Remington’s Pharmaceutical Sciences, latest edition
Chemical Formulary of Formulations
Pharmacognosy books and manuals
Quantitative Pharmaceutical Chemistry books authored by Jenkin’s etal
Pharmaceutical Dosage Forms and Drug Delivery Systems by Howard Ansel
Books on Chemical Investigation of Plants, authored by L. Rosenthaler
Journals and Magazines on Plants or Herbal Medicines
Tuesday, November 17, 2009
sylabus(jurisprudence)
A Syllabus for the Proposed Pharmacy Curriculum SY 2005-2006
Course Title: PHARMACEUTICAL JURISPRUDENCE & ETHICS
Course Number: Phar. Ad. I
Course Description: The course deals with the study of legal rules and regulations as applied to pharmacy and Pharmacy practice. It also embodies a code of ethics of the profession.
Prerequisite(s): Bioethics/ Christian Ethics, Hospital Pharmacy, Pharmaceutics 2
Credit: 3 Units
Placement: 4th year, 2nd semester
General Objectives: At the end of the course, the students should be able to:
1. acquire a theoretical and practical knowledge regarding the legal and ethical control of the pharmacy education and the practice of the profession;
2. identify the rights and duties of the pharmacists towards the public, colleagues, pharmacy assistants, physicians and other allied medical professionals;
3. appraise the different provisions of the laws concerning the pharmaceutical education and profession.
First Grading Period
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tools
At the end of the chapter, the student should be able to:
1. discuss the legal and ethical controls of the pharmacy practice;
2. develop a sense of responsibility in following the code of ethics for pharmacists;
3. explain the importance of good governance for the professionals.
At the end of the chapter, the student should be able to:
1. state the laws, administrative orders, and regulations related to the pharmacy education and profession;
2. identify the delimitation of the practice of pharmacy in the Philippines; I. Introduction to Pharmacy
Jurisprudence and Ethics
1. Legal and Ethical Control of the Pharmacy Practice
2. Code of Ethics for Pharmacists
3. Oath of a Pharmacist
4. Code of Good Governance for the Professionals
II. Standards of the Practice of
Pharmacy and Pharmaceutical Education
1. Republic Act. No. 5921 “The Pharmacy Law” as amended by Executive Order No. 174
2. Higher Education Act 15 hours Lecture
Classroom discussion
Case Analysis
Group presentation
a. Case Analysis
b. Role Playing
Quizzes
Assignments
Examinations
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tools
3. discuss the importance of continuing professional education in the practice of pharmacy.
Second Grading Period
Specific Objectives Topics Time Alloted Teaching Strategies Evaluation Tools
At the end of the chapter, the student should be able to:
1. familiarize and explain the different Presidential Decrees, Executive Orders, Administrative Orders, and rules and guidelines pertaining to food, drug, devices and cosmetics;
2. outline the organization and enumerate the functions of the BFAD;
3. explain the need to apply and observe CGMP in the manufacturing, processing, packaging or holding of foods, drugs, devices and cosmetics;
4. list the requirements for labeling and registration of pharmaceutical products;
5. enumerate the requirements for the licensing of drug establishments and outlets;
6. discuss the law on counterfeit drugs. III. Standards for Food, Drug,
Devices and Cosmetics
1. Republic Act No. 3270 “Foods, Drugs, Devices and Cosmetics Act” as amended by Executive No.175
2. DOH and BFAD Administrative Orders/ Executive Orders/ Memorandum Circulars/ Presidential Decree/ Bureau Circular
3. Republic Act No. 8203 “Special Law on Counterfeit Drugs”
15 hours Lecture
Classroom discussion
Case Analysis
Group presentation
Film showing
Role playing Quizzes
Examinations
Reaction paper
Graded recitation
Graded assignment
Third/ Final Grading Period
Specific Objectives Topics Time Alloted Teaching Strategies Evaluation Tools
At the end of the chapter, the student should be able to:
1. state the National Drug Policies and explain the importance of its creation;
2. discuss the Generics Act of 1988 and its implementing rules and regulations; IV. Ensure Affordability and Accessibility of Drugs
1. The Primer on the National Drug Policy
2. Republic Act No. 6675 “Generics Act of 1988” 15 hours Lecture
Classroom discussion
Case analysis Quizzes
Examinations
Reaction paper
Specific Objectives Topics Time Alloted Teaching Strategies Evaluation Tools
3. explain the importance of the creation of RA 7432 and RA 9275, and the responsibilities of the pharmacists in implementing the provisions of the law;
4. recite the different rights of the consumers.
At the end of the chapter, the student should be able to:
1. paraphrase the provisions of the Comprehensive Dangerous Drugs Act of 2002 (RA 9165);
2. summarize the laws, administrative orders and regulations pertaining to dangerous drugs in the Philippines
3. DOH and BFAD Administrative Orders
4. Republic Act No. 7432 “Senior Citizens Act”
5. Republic Act No. 9275 “Expanded Senior Citizens Act”
6. Republic Act No. 7394 “The Consumers Act of the Philippines”
7. Republic Act No. 7581 “The Price Act”
V. Control of the Use of Dangerous Drugs
1. Republic Act No. 9165 “The Comprehensive Dangerous Drugs Act of 2002”;
2. Implementing Rules and Regulations of RA 9165 Debate
Group presentation
Film showing
Lecture
Class discussion
Debate
Film showing
Role playing
Case analysis Graded recitation
Graded assignment
Quizzes
Examinations
Reaction paper
Graded recitation
Graded assignment
References: Bureau of Food and Drugs and Philippine National Drug Policy Program – Facilities, Functions and Capabilities. DOH, Manilia
BFAD – Drug Related Administrative Orders and Memorandum Circulars (with Summaries and Annotations), DOH. Manila. 1982
Comprehensive Dangerous Drugs Act of the 2002, DDB, Manila. 2002
The Consumers Act of the Philippines, RA 7394, Reprinted by the BFAD and DOH, DOH Complex, Alabang, Muntinlupa
Philippine National Drug Formulary – Essential Drug List, vol. 1, 5th ed., DOH, Manila, 2000
Reference Manual on the Philippine National Drug Policy and the Generics Act of 1988, DOH, Manila -1991
Seminar Workshop on Monitoring and Enforcement (RA7581)
Textbooks: Hizon, Flora. Notes on Pharmaceutical Jurisprudence and Ethics. UST
Limuaco, Olivia M. and Emma G. Peña. Pharmaceutical Jurisprudence and Ethics.
Limuaco, Olivia M. and Mary Jane C. Cruz. Pharmaceutical Jurisprudence and Ethics. 4th ed., Manila. 2003
Course Title: PHARMACEUTICAL JURISPRUDENCE & ETHICS
Course Number: Phar. Ad. I
Course Description: The course deals with the study of legal rules and regulations as applied to pharmacy and Pharmacy practice. It also embodies a code of ethics of the profession.
Prerequisite(s): Bioethics/ Christian Ethics, Hospital Pharmacy, Pharmaceutics 2
Credit: 3 Units
Placement: 4th year, 2nd semester
General Objectives: At the end of the course, the students should be able to:
1. acquire a theoretical and practical knowledge regarding the legal and ethical control of the pharmacy education and the practice of the profession;
2. identify the rights and duties of the pharmacists towards the public, colleagues, pharmacy assistants, physicians and other allied medical professionals;
3. appraise the different provisions of the laws concerning the pharmaceutical education and profession.
First Grading Period
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tools
At the end of the chapter, the student should be able to:
1. discuss the legal and ethical controls of the pharmacy practice;
2. develop a sense of responsibility in following the code of ethics for pharmacists;
3. explain the importance of good governance for the professionals.
At the end of the chapter, the student should be able to:
1. state the laws, administrative orders, and regulations related to the pharmacy education and profession;
2. identify the delimitation of the practice of pharmacy in the Philippines; I. Introduction to Pharmacy
Jurisprudence and Ethics
1. Legal and Ethical Control of the Pharmacy Practice
2. Code of Ethics for Pharmacists
3. Oath of a Pharmacist
4. Code of Good Governance for the Professionals
II. Standards of the Practice of
Pharmacy and Pharmaceutical Education
1. Republic Act. No. 5921 “The Pharmacy Law” as amended by Executive Order No. 174
2. Higher Education Act 15 hours Lecture
Classroom discussion
Case Analysis
Group presentation
a. Case Analysis
b. Role Playing
Quizzes
Assignments
Examinations
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tools
3. discuss the importance of continuing professional education in the practice of pharmacy.
Second Grading Period
Specific Objectives Topics Time Alloted Teaching Strategies Evaluation Tools
At the end of the chapter, the student should be able to:
1. familiarize and explain the different Presidential Decrees, Executive Orders, Administrative Orders, and rules and guidelines pertaining to food, drug, devices and cosmetics;
2. outline the organization and enumerate the functions of the BFAD;
3. explain the need to apply and observe CGMP in the manufacturing, processing, packaging or holding of foods, drugs, devices and cosmetics;
4. list the requirements for labeling and registration of pharmaceutical products;
5. enumerate the requirements for the licensing of drug establishments and outlets;
6. discuss the law on counterfeit drugs. III. Standards for Food, Drug,
Devices and Cosmetics
1. Republic Act No. 3270 “Foods, Drugs, Devices and Cosmetics Act” as amended by Executive No.175
2. DOH and BFAD Administrative Orders/ Executive Orders/ Memorandum Circulars/ Presidential Decree/ Bureau Circular
3. Republic Act No. 8203 “Special Law on Counterfeit Drugs”
15 hours Lecture
Classroom discussion
Case Analysis
Group presentation
Film showing
Role playing Quizzes
Examinations
Reaction paper
Graded recitation
Graded assignment
Third/ Final Grading Period
Specific Objectives Topics Time Alloted Teaching Strategies Evaluation Tools
At the end of the chapter, the student should be able to:
1. state the National Drug Policies and explain the importance of its creation;
2. discuss the Generics Act of 1988 and its implementing rules and regulations; IV. Ensure Affordability and Accessibility of Drugs
1. The Primer on the National Drug Policy
2. Republic Act No. 6675 “Generics Act of 1988” 15 hours Lecture
Classroom discussion
Case analysis Quizzes
Examinations
Reaction paper
Specific Objectives Topics Time Alloted Teaching Strategies Evaluation Tools
3. explain the importance of the creation of RA 7432 and RA 9275, and the responsibilities of the pharmacists in implementing the provisions of the law;
4. recite the different rights of the consumers.
At the end of the chapter, the student should be able to:
1. paraphrase the provisions of the Comprehensive Dangerous Drugs Act of 2002 (RA 9165);
2. summarize the laws, administrative orders and regulations pertaining to dangerous drugs in the Philippines
3. DOH and BFAD Administrative Orders
4. Republic Act No. 7432 “Senior Citizens Act”
5. Republic Act No. 9275 “Expanded Senior Citizens Act”
6. Republic Act No. 7394 “The Consumers Act of the Philippines”
7. Republic Act No. 7581 “The Price Act”
V. Control of the Use of Dangerous Drugs
1. Republic Act No. 9165 “The Comprehensive Dangerous Drugs Act of 2002”;
2. Implementing Rules and Regulations of RA 9165 Debate
Group presentation
Film showing
Lecture
Class discussion
Debate
Film showing
Role playing
Case analysis Graded recitation
Graded assignment
Quizzes
Examinations
Reaction paper
Graded recitation
Graded assignment
References: Bureau of Food and Drugs and Philippine National Drug Policy Program – Facilities, Functions and Capabilities. DOH, Manilia
BFAD – Drug Related Administrative Orders and Memorandum Circulars (with Summaries and Annotations), DOH. Manila. 1982
Comprehensive Dangerous Drugs Act of the 2002, DDB, Manila. 2002
The Consumers Act of the Philippines, RA 7394, Reprinted by the BFAD and DOH, DOH Complex, Alabang, Muntinlupa
Philippine National Drug Formulary – Essential Drug List, vol. 1, 5th ed., DOH, Manila, 2000
Reference Manual on the Philippine National Drug Policy and the Generics Act of 1988, DOH, Manila -1991
Seminar Workshop on Monitoring and Enforcement (RA7581)
Textbooks: Hizon, Flora. Notes on Pharmaceutical Jurisprudence and Ethics. UST
Limuaco, Olivia M. and Emma G. Peña. Pharmaceutical Jurisprudence and Ethics.
Limuaco, Olivia M. and Mary Jane C. Cruz. Pharmaceutical Jurisprudence and Ethics. 4th ed., Manila. 2003
Syllabus(Manufacturing Pharmacy)
A Syllabus for the Proposed Pharmacy Curriculum SY 2005-2006
Course Title : Manufacturing Pharmacy
Course Number : Pharmaceutics II
Credit Units : 3 units (lecture) / 2 units (laboratory)
Course Description : This course presents the basic principles, methods and technology involved in the production of various drug dosage forms and delivery systems, from the initial design of the dosage forms to their actual manufacture, including the requirements for packaging, equipment and facilities.
Prerequisite(s) : Pharmaceutics I and Physical Pharmacy
Placement : 3rd year, 2nd semester
General Objectives : At the end of the course, the students should be able to:
1. enumerate and discuss the requirements for facilities, equipment, methods and processes, organization and personnel as specified in the Current Good Manufacturing Practices (CGMPs);
2. outline the different pharmaceutical unit operations;
3. describe the principles and technology involved in the design, formulation, manufacture and packaging of the various drug dosage forms and delivery systems;
4. discuss how adjuvant ingredients, technological procedures, and material physical and chemical properties affect the formulation, design and production of the various drug dosage forms.
Course Outline :
First Grading Period
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
At the end of the chapter, the students should be able to:
1. identify and describe the functions of the different departments/sections in a pharmaceutical firm;
A. Organizational structure of a pharmaceutical company
B. Current Good Manufacturing Practices (CGMPs)
C. Preformulation Process 15 hours Lecture with audio-visual presentation
Class discussion
Written examinations, assignments, quizzes, graded recitation
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
2. discuss the importance of CGMPs;
3. explain the importance of preformulation in the production of medicines;
4. describe the general pharmaceutical plant design conforming to the provisions of the CGMPs;
discuss the proper system in handling pharmaceutical materials. A. General pharmaceutical plant design and construction, room classification based on air particle density, environmental control (humidity, temperature and air-conditioning), and industrial hazards and safety.
B. Material handling systems for solids, liquids and gas
Second Grading Period
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
At the end of the chapter, the students should be able to:
1. cite and discuss the different unit operations and equipment for pharmaceutical production;
2. identify and describe the specific production facilities, raw materials used in the formulations and methods of manufacturing the various dosage forms;
3. integrate CGMP in the manufacture of pharmaceutical dosage forms. C. Pharmaceutical unit operations and equipment: milling, granulation and size separation; mixing; filtration; drying
D. Facilities, materials, methods and technology in the design, formulation and production of various dosage forms:
1. Solid dosage forms:
a. Tablets (immediate release and controlled release)
b. Capsules
2. Non-sterile liquid dosage forms:
a. solutions
b. suspensions and lotions
c. emulsions
3. Semi-solid dosage forms and other topical products:
a. ointments
b. creams
c. gel 15 hours Lecture with audio-visual presentation
Class discussion
Written examinations, assignments, quizzes, graded recitation
Final Grading Period
At the end of the chapter, the students should be able to:
1. identify and describe the specific production facilities, raw materials used in the formulations and methods of manufacturing the various dosage forms;
2. describe different methods of sterilization;
3. explain the importance of depyrogenation in the preparation of sterile products;
4. discuss the formulation and production technology of cosmetics;
5. discuss the packaging principles and technology in cosmetics. 6. Aerosols and inhalations
7. Sterile products and ophthalmic preparations
8. Implantable preparations
9. Transdermal drug delivery systems
G. Cosmetics
1. Lipstick
2. Shampoo
3. Face powder
4. Soap
5. Toothpaste 15 hours Lecture with audio-visual presentation
Class discussion
Written examinations, assignments, quizzes, graded recitation
References : H. Ansel, L. Allen Jr., N. Popovich. Pharmaceutical Dosage Forms and Drug Delivery Systems
WHO’s Good Manufacturing Practice and Inspection
A. Wade and P.J. Walker. Handbook of Pharmaceutical Excipients
A. Gennaro. Remington: the Science and Practice of Pharmacy. Latest Edition.
S. Turco. Sterile Dosage Form. 4th Edition
L. Lachman, et.al. The Theory and Practice of Industrial Pharmacy. 3rd Edition.
G.S. Banker and C.T. Rhodes. Modern Pharmaceutics. 4th Edition.
Course Title : Manufacturing Pharmacy
Course Number : Pharmaceutics II
Credit Units : 3 units (lecture) / 2 units (laboratory)
Course Description : This course presents the basic principles, methods and technology involved in the production of various drug dosage forms and delivery systems, from the initial design of the dosage forms to their actual manufacture, including the requirements for packaging, equipment and facilities.
Prerequisite(s) : Pharmaceutics I and Physical Pharmacy
Placement : 3rd year, 2nd semester
General Objectives : At the end of the course, the students should be able to:
1. enumerate and discuss the requirements for facilities, equipment, methods and processes, organization and personnel as specified in the Current Good Manufacturing Practices (CGMPs);
2. outline the different pharmaceutical unit operations;
3. describe the principles and technology involved in the design, formulation, manufacture and packaging of the various drug dosage forms and delivery systems;
4. discuss how adjuvant ingredients, technological procedures, and material physical and chemical properties affect the formulation, design and production of the various drug dosage forms.
Course Outline :
First Grading Period
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
At the end of the chapter, the students should be able to:
1. identify and describe the functions of the different departments/sections in a pharmaceutical firm;
A. Organizational structure of a pharmaceutical company
B. Current Good Manufacturing Practices (CGMPs)
C. Preformulation Process 15 hours Lecture with audio-visual presentation
Class discussion
Written examinations, assignments, quizzes, graded recitation
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
2. discuss the importance of CGMPs;
3. explain the importance of preformulation in the production of medicines;
4. describe the general pharmaceutical plant design conforming to the provisions of the CGMPs;
discuss the proper system in handling pharmaceutical materials. A. General pharmaceutical plant design and construction, room classification based on air particle density, environmental control (humidity, temperature and air-conditioning), and industrial hazards and safety.
B. Material handling systems for solids, liquids and gas
Second Grading Period
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
At the end of the chapter, the students should be able to:
1. cite and discuss the different unit operations and equipment for pharmaceutical production;
2. identify and describe the specific production facilities, raw materials used in the formulations and methods of manufacturing the various dosage forms;
3. integrate CGMP in the manufacture of pharmaceutical dosage forms. C. Pharmaceutical unit operations and equipment: milling, granulation and size separation; mixing; filtration; drying
D. Facilities, materials, methods and technology in the design, formulation and production of various dosage forms:
1. Solid dosage forms:
a. Tablets (immediate release and controlled release)
b. Capsules
2. Non-sterile liquid dosage forms:
a. solutions
b. suspensions and lotions
c. emulsions
3. Semi-solid dosage forms and other topical products:
a. ointments
b. creams
c. gel 15 hours Lecture with audio-visual presentation
Class discussion
Written examinations, assignments, quizzes, graded recitation
Final Grading Period
At the end of the chapter, the students should be able to:
1. identify and describe the specific production facilities, raw materials used in the formulations and methods of manufacturing the various dosage forms;
2. describe different methods of sterilization;
3. explain the importance of depyrogenation in the preparation of sterile products;
4. discuss the formulation and production technology of cosmetics;
5. discuss the packaging principles and technology in cosmetics. 6. Aerosols and inhalations
7. Sterile products and ophthalmic preparations
8. Implantable preparations
9. Transdermal drug delivery systems
G. Cosmetics
1. Lipstick
2. Shampoo
3. Face powder
4. Soap
5. Toothpaste 15 hours Lecture with audio-visual presentation
Class discussion
Written examinations, assignments, quizzes, graded recitation
References : H. Ansel, L. Allen Jr., N. Popovich. Pharmaceutical Dosage Forms and Drug Delivery Systems
WHO’s Good Manufacturing Practice and Inspection
A. Wade and P.J. Walker. Handbook of Pharmaceutical Excipients
A. Gennaro. Remington: the Science and Practice of Pharmacy. Latest Edition.
S. Turco. Sterile Dosage Form. 4th Edition
L. Lachman, et.al. The Theory and Practice of Industrial Pharmacy. 3rd Edition.
G.S. Banker and C.T. Rhodes. Modern Pharmaceutics. 4th Edition.
clin toxi syllabus
A Syllabus for the Proposed Pharmacy Curriculum
Course Title : Clinical Toxicology
Course Number :
Credit Units : 3 units (2 units lecture, 1 unit laboratory), 4th year 1st sem
Course Description : The fundamentals of clinical toxicology including a study of the general classes of toxic agents, mechanism of toxicity, target organ toxicity, management, and their detection.
Prerequisite(s) : Pharmacology 1 , Pharmacology 2 (corequisite)
General Objectives : At the end of the course,
1. The students should acquire basic knowledge in the origin and type of exposure, stages in the induction of toxicity and evidences in poisoning.
2. The students should be able to identify the commonly encountered deleterious chemicals and drugs to man and his environment.
3. To manifest the pharmacist responsibility in the risk assessment and management of poisoning
Course Outline :
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
At the end of the course, the student must be able to:
1. Discuss and explain important concepts in toxicology (toxicodynamics, toxicokinetics, teratology, carcinogenesis, occupational toxicology, environmental toxicology and organ toxicology)
2. Identify important information regarding the specific poisons and toxic agents like the mechanism of toxic action, toxic effects and symptomatology, management and resources.
A. General Concepts
1. Introduction
a. Definition of toxicology and its importance in the practice of pharmacy
b. Definition of terms
c. Areas in Toxicoloy
2. Toxicodynamics
3. Toxicokinetics
a. Dose-Response Relationship (LD50, LOAEL & NOAEL)
Lectures with Audio-visual Aids (Powerpoint)
Group dynamics
Pre and Post Quizzes
Oral Exams and/or graded recitations on assigned topics
Performance in the Written Examinations
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
3. Assess and solve basic clinical problems in relation to toxicology.
4. Identify chemicals that commonly cause poisoning through laboratory tests.
5. Demonstrate the proper techniques and observe precautions in handling and identifying poisons or potential poisons.
6. Properly handle animals (e.g. guinea pig, mouse) for chemical analysis of poisons in the laboratory.
B. Clinical Toxicology
1. Principles of Clinical Toxicology
2. General Management of a Suspected Poisoned Patient
a. Emergency stabilization
b. Clinical evaluation
c. Elimination of the poison
d. Excretion of absorbed substances
e. Antidotes
f. Supportive therapy
g. Disposition
3. Management of Specific Poisons
a. Therapeutic agents
i. Analgesics
ii. Anti-infective drugs
iii. Cardiovascular drugs
1. Antihypertensive
2. Antiarrythmics
3. Lipid-lowering drugs
iv. CNS drugs
1. Anticonvulsants
v. Psychotropic agents
1. Antidepressants
2. MAOI
3. Neuroleptic agents
4. Sedative-hypnotic drugs
vi. Respiratory drugs
vii. GI drugs
viii. Endocrine drugs
b. Drugs of Abuse
i. Opiates
ii. Amphetamine (diet pills, cough syrups)
iii. Marijuana and cannabinoids
iv. Hallucinogenic drugs
Lectures with Audio-visual Aids (Powerpoint)
Group dynamics
Pre and Post Quizzes
Oral Exams and/or graded recitations on assigned topics
Performance in the Written Examinations
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
c. Household Poisons
d. Pesticides
e. Heavy metals
f. Inhalatory Poisons
g. Environmental Poisons
References :
Prepared by :Marybelen T. Mogol, RPh.,MSPharm
Course Title : Clinical Toxicology
Course Number :
Credit Units : 3 units (2 units lecture, 1 unit laboratory), 4th year 1st sem
Course Description : The fundamentals of clinical toxicology including a study of the general classes of toxic agents, mechanism of toxicity, target organ toxicity, management, and their detection.
Prerequisite(s) : Pharmacology 1 , Pharmacology 2 (corequisite)
General Objectives : At the end of the course,
1. The students should acquire basic knowledge in the origin and type of exposure, stages in the induction of toxicity and evidences in poisoning.
2. The students should be able to identify the commonly encountered deleterious chemicals and drugs to man and his environment.
3. To manifest the pharmacist responsibility in the risk assessment and management of poisoning
Course Outline :
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
At the end of the course, the student must be able to:
1. Discuss and explain important concepts in toxicology (toxicodynamics, toxicokinetics, teratology, carcinogenesis, occupational toxicology, environmental toxicology and organ toxicology)
2. Identify important information regarding the specific poisons and toxic agents like the mechanism of toxic action, toxic effects and symptomatology, management and resources.
A. General Concepts
1. Introduction
a. Definition of toxicology and its importance in the practice of pharmacy
b. Definition of terms
c. Areas in Toxicoloy
2. Toxicodynamics
3. Toxicokinetics
a. Dose-Response Relationship (LD50, LOAEL & NOAEL)
Lectures with Audio-visual Aids (Powerpoint)
Group dynamics
Pre and Post Quizzes
Oral Exams and/or graded recitations on assigned topics
Performance in the Written Examinations
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
3. Assess and solve basic clinical problems in relation to toxicology.
4. Identify chemicals that commonly cause poisoning through laboratory tests.
5. Demonstrate the proper techniques and observe precautions in handling and identifying poisons or potential poisons.
6. Properly handle animals (e.g. guinea pig, mouse) for chemical analysis of poisons in the laboratory.
B. Clinical Toxicology
1. Principles of Clinical Toxicology
2. General Management of a Suspected Poisoned Patient
a. Emergency stabilization
b. Clinical evaluation
c. Elimination of the poison
d. Excretion of absorbed substances
e. Antidotes
f. Supportive therapy
g. Disposition
3. Management of Specific Poisons
a. Therapeutic agents
i. Analgesics
ii. Anti-infective drugs
iii. Cardiovascular drugs
1. Antihypertensive
2. Antiarrythmics
3. Lipid-lowering drugs
iv. CNS drugs
1. Anticonvulsants
v. Psychotropic agents
1. Antidepressants
2. MAOI
3. Neuroleptic agents
4. Sedative-hypnotic drugs
vi. Respiratory drugs
vii. GI drugs
viii. Endocrine drugs
b. Drugs of Abuse
i. Opiates
ii. Amphetamine (diet pills, cough syrups)
iii. Marijuana and cannabinoids
iv. Hallucinogenic drugs
Lectures with Audio-visual Aids (Powerpoint)
Group dynamics
Pre and Post Quizzes
Oral Exams and/or graded recitations on assigned topics
Performance in the Written Examinations
Specific Objectives Topics Time Allotted Teaching Strategies Evaluation Tool
c. Household Poisons
d. Pesticides
e. Heavy metals
f. Inhalatory Poisons
g. Environmental Poisons
References :
Prepared by :Marybelen T. Mogol, RPh.,MSPharm
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