CLINICAL TOXICOLOGY

Sample questions
REMINDER: STRICTLY NO ERASURES.
Test I- Multiple Choice: Encircle the letter of your choice:
1. the quantity of medicine that can kill an organism:
a. fatal dose b. LD50 c. teratology
2. the evidences to be saved in non fatal poisoning are the following, except:
a. lungs b. urine c. food d. blood e. body fat
3. most accidental poisoning in children is caused by:
a. crayons b. bleaches c. detergents d. insecticides
4. evidence obtained from an examination of the tissues and organs of the dead:
a. chemical b. experimental c. post mortem d. circumstantial
5. antidote for iodine poisoning:
a. AgNO3 b. starch c. sugar d, potassium nitrate
6. a poison which increases suddenly in its intensity of action after slow or gradual addition of it is:
a. corrosive b. cumulative c. true d. irritant
7. a specialized field of toxicology that designates an area of professional; emphasis within the realm of medical science.
a. forensic b. clinical c. environmental d. regulatory
8. streptomycin can cause:
a. 4th cranial damage b. 7th cranial c. 8th cranial
9. dryness of the mouth is a side effect of:
a. atropine b. aspirin c. acetaminophen d. cimetidine
10. nail polish remover contains:
a. aniline b. acetone c. NH4OH d. Phosphoric acid
11. the major route by which toxic agents gain access to the body are through the ff except:
a. blood b. GIT c. lungs d. skin
12. constipation caused by active charcoal can be relieved by concomitant administration of:
a. glycerol b. water c. laxative d. NOTA
13. methylene blue is the antidote for:
a.aniline b. iodine c. cyanide d. nitrite
14. it is the most toxic metal:
a. nitrite b. oxalate c. arsenic d. beryllium
15. ammonium salt is the antidote for:
a. aniline b. cyanide c. iodine d. formaldehyde
16. it is the choice of professional poisoners:
a. nitrite b. oxalate c. arsenic d. beryllium
17. it is used in fingerfrint photography:
a. nitrite b. mercury c. arsenic d. nitrite
18. it is used to preserve the color of meat in pickling:
a. nitrite b. oxalate c. lead d. mercury
19. it is the poison found in rust and ink eradicator.
a. oxalate b. nitrite c. mercury d. lead
20. used in silvering of mirror & it causes metal line gum:
a. bismuth b. boron c. cadmium d. chromium
21. its deficiency mimics diabetes mellitus, it is found in brown sugar & butter:
a. bismuth b. boron c. chromium d.cesium
22. used in the manufacture of smoke bomb, antiseborrheic shampoos, in the treatment of bone fracture & rickets:
a. cadmium b. boron c. cesium d. bismuth
23. it is also known as the stink damp:
a. H2S b. CO c. CS2 d. N2O
24. known as the neutral spirit:
a. aniline b. cyanide c. ethyl alcohol d. iodine
25. these are simple asphyxiants which are gases, except;
a. ethanol b. methane c. nitrogen d. none
26. fatal dose of aspirin:
a. 5 grams b. 5 grains c. 5 mg d. all of these
27. known as the rodent poison:
a.H2S b. CO c. C2S d. phosphorus
28.toxic substance found in tulingan:
a. sourine b. venerupin c. gemblid d. potassium bromate

29. poison found in toilet bowl cleaner:
a. nitrite b. lead c. nitite d. napthalene
30. toxic substance found in pandesal, cakes & other bakery products:
a. venerupin b. gemblid c. sourine d. potassium bromate
31. lead can be effectively detoxified by:
a. barium sulfate b. BAL with EDTA c. ethanol
32. induction of vomiting is accomplished by administering:
a. syrup of ipecac b. ginger ale c. peppermint syrup
33. mushroom poisoning comes from:
a. belladonna b.digitalis c. amanita phalloides
34. causes of minamata disease:
a. mercury b. cadmium c. iron d. nitrite
35. enters the breast milk and can cause neonatal narcotic dependence:
a. heroin b. codeine c. both a & b d. none
36. an agent that neutralizes a poison or counteract its effect is a/an:
a. antidote b. antiemetic c. antibiotic d. counterirritant
37. the major target organ of toxicity of benzene:
a. blood b. liver c. bone marrow d. heart
38. antipyrine has been known to cause:
a. blood dyscrasias b.high incidence of rashes
39. the following are important air pollutants except:
a. carbon monoxide b.malathion c. sulfur dioxide
40. angina pectoris is a type of pain seen in this type of poisoning:
a. HCl b. lead c. nicotine d. mercury
41. causes fetal hydantoin syndrome:
a. heroin b. phenytoin c. penicillin d. tamoxifen
42. toxic metabolite of CCl4:
a. epoxides b. phosgene c. nitrite d. cyanide
43. angel dust:
a. MDMA b. LSD c. PCP d. THC
44. present in tear gas:
a. cyanide b. capsaicin c. alloin d. cysteine sulfoxide
45. roofies:
a. alprazolam b. cannabis c. flunitrazepam
46. examples of herbicides, except:
a. phenoxyacetic acid b.paraquat c. nicotine
47. it causes shellfish toxicity:
a. dinoflagellates b.snails c. jellyfish
48. cobra venom is composed of:
a. toxin b. phytotoxin c. bufotoxin d. syntoxin
49. cocaine is commonly called :
a. coke b. lady c. crystals d. all of the above
50. entrance or outlet of any body cavity is termed as:
a. media b. meatus c. oral d. orifice

Test II- Matching type :Match the Medications and their Antidotes: Write the letter Only. Take note of the CAPITAL LETTER/s.
_____1. Acetaminophen A. Naloxone
_____2. Benzodiazepines B. Acetylcysteine
_____3. Digoxin C. Flumazenil
_____4. Dopamine D. Phentolamine
_____5. Heparin E. Leucovorin
_____6. Iron F. Digoxine immune FAB
_____7. Methotrexate G. Protamine
_____8. Morphine H. Deferoxamine
_____9. Nitrogen mustard I. Sodium Thiosulfate
____10. Warfarin J. Vitamin K/ Phytonadione

Test III- True or False: write YES if the statement is correct, NO, if it is wrong.
NO ERASURES ALLOWED.
_____1. almost every poison has been known to produce convulsive effect, but the only true convulsive poison s are the alkaloids of the strychnos class.
_____2. volatile poisons volatilizes w/o decomposition when heated & distill from an acid solution.
_____3. non-volatile organic poisons do not distill from acid solution.
_____4. metallic poisons include all poisonous metals such as arsenic, antimony, copper, mercury & silver.
_____5. post mortem appearance of blood is fluid & dark & may contain a fewclots.
_____6. the death beginning at heart is asphyxia
____¬_7. the death beginning at lungs is coma.
_____8. the death beginning brain is syncope.
_____9. coma is a condition usually dependent upon the brain.
_____10. coma maybe defined as state of profound insensibility.
_____11. deliriants are agents that affect the brain
_____12. washing is often advisable even after free vomiting as some adhere to stomach walls.
_____13. a corrosive poison is one w/c act chiefly in the diluted state upon the nervous system.
_____14. deliriants are agents w/c produced exhaustioned & cause marked loss of vital or muscular power.
_____15. poisons affect the heart & cause death by sudden shock, collapse , or syncope.
_____16. when active measures are to be employed to evacuate , the stomach pump should be employed.
_____17. in poisoning, it is better to use almost any emetic at once than to lose valuable time in getting just enough/ right emetic.
_____18. the action of an emetic is aided by giving plenty of cold water.
_____19. it was dioscorides who ist to refuse the nature of poisons.
_____20. toxicology has been developed fr the greek word “toxicon”
_____21. an organ thru which nearly all the poisons are eliminated is the lungs
_____22. all poisons have their properties to fix or anchor themselves to certain tissues of the body.
_____ 23. gaseous poisons are not deposited but promptly removed by way of the lungs.
_____ 24. symptoms of food poisoning are usually those of a gastric intestinal irritation.
_____ 25. there is no known distinctive chemical test for certain poisons.

Test IV- Enumeration: Please write the answers at the last page space provided for:
A. Four (4 ) Evidences of Poisoning:
B. Three (3) Universal Antidotes
C. Three(3) effects of Poison:
D. Two (2) Types of Poisoning______
E. Three (3) Classification of Poisons: